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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We report the effects of lifelong treatment of mice wit...

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Detalles Bibliográficos
Autores principales: Strong, Randy, Miller, Richard A., Antebi, Adam, Astle, Clinton M., Bogue, Molly, Denzel, Martin S., Fernandez, Elizabeth, Flurkey, Kevin, Hamilton, Karyn L., Lamming, Dudley W., Javors, Martin A., de Magalhães, João Pedro, Martinez, Paul Anthony, McCord, Joe M., Miller, Benjamin F., Müller, Michael, Nelson, James F., Ndukum, Juliet, Rainger, G. Ed., Richardson, Arlan, Sabatini, David M., Salmon, Adam B., Simpkins, James W., Steegenga, Wilma T., Nadon, Nancy L., Harrison, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013015/
https://www.ncbi.nlm.nih.gov/pubmed/27312235
http://dx.doi.org/10.1111/acel.12496