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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer
The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We report the effects of lifelong treatment of mice wit...
Autores principales: | Strong, Randy, Miller, Richard A., Antebi, Adam, Astle, Clinton M., Bogue, Molly, Denzel, Martin S., Fernandez, Elizabeth, Flurkey, Kevin, Hamilton, Karyn L., Lamming, Dudley W., Javors, Martin A., de Magalhães, João Pedro, Martinez, Paul Anthony, McCord, Joe M., Miller, Benjamin F., Müller, Michael, Nelson, James F., Ndukum, Juliet, Rainger, G. Ed., Richardson, Arlan, Sabatini, David M., Salmon, Adam B., Simpkins, James W., Steegenga, Wilma T., Nadon, Nancy L., Harrison, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013015/ https://www.ncbi.nlm.nih.gov/pubmed/27312235 http://dx.doi.org/10.1111/acel.12496 |
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