Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein

The mechanistic relationship between amyloid β1‐42 (Aβ1‐42) and the alteration of Tau protein are debated. We investigated the effect of Aβ1‐42 monomers and oligomers on Tau, using mice expressing wild‐type human Tau that do not spontaneously develop Tau pathology. After intraventricular injection o...

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Detalles Bibliográficos
Autores principales: Manassero, Giusi, Guglielmotto, Michela, Zamfir, Raluca, Borghi, Roberta, Colombo, Laura, Salmona, Mario, Perry, George, Odetti, Patrizio, Arancio, Ottavio, Tamagno, Elena, Tabaton, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013016/
https://www.ncbi.nlm.nih.gov/pubmed/27406053
http://dx.doi.org/10.1111/acel.12500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013016/
https://www.ncbi.nlm.nih.gov/pubmed/27406053
http://dx.doi.org/10.1111/acel.12500

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