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Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

Neurodegenerative diseases are distinguished by characteristic protein aggregates initiated by disease‐specific ‘seed’ proteins; however, roles of other co‐aggregated proteins remain largely unexplored. Compact hippocampal aggregates were purified from Alzheimer's and control‐subject pools usin...

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Detalles Bibliográficos
Autores principales: Ayyadevara, Srinivas, Balasubramaniam, Meenakshisundaram, Parcon, Paul A., Barger, Steven W., Griffin, W. Sue T., Alla, Ramani, Tackett, Alan J., Mackintosh, Samuel G., Petricoin, Emanuel, Zhou, Weidong, Shmookler Reis, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013017/
https://www.ncbi.nlm.nih.gov/pubmed/27448508
http://dx.doi.org/10.1111/acel.12501