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Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls
Neurodegenerative diseases are distinguished by characteristic protein aggregates initiated by disease‐specific ‘seed’ proteins; however, roles of other co‐aggregated proteins remain largely unexplored. Compact hippocampal aggregates were purified from Alzheimer's and control‐subject pools usin...
Autores principales: | Ayyadevara, Srinivas, Balasubramaniam, Meenakshisundaram, Parcon, Paul A., Barger, Steven W., Griffin, W. Sue T., Alla, Ramani, Tackett, Alan J., Mackintosh, Samuel G., Petricoin, Emanuel, Zhou, Weidong, Shmookler Reis, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013017/ https://www.ncbi.nlm.nih.gov/pubmed/27448508 http://dx.doi.org/10.1111/acel.12501 |
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