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K(Ca)3.1 upregulation preserves endothelium‐dependent vasorelaxation during aging and oxidative stress

Endothelial oxidative stress develops with aging and reactive oxygen species impair endothelium‐dependent relaxation (EDR) by decreasing nitric oxide (NO) availability. Endothelial K(Ca)3.1, which contributes to EDR, is upregulated by H(2)O(2). We investigated whether K(Ca)3.1 upregulation compensat...

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Detalles Bibliográficos
Autores principales: Choi, Shinkyu, Kim, Ji Aee, Li, Hai‐yan, Shin, Kyong‐Oh, Oh, Goo Taeg, Lee, Yong‐Moon, Oh, Seikwan, Pewzner‐Jung, Yael, Futerman, Anthony H., Suh, Suk Hyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013018/
https://www.ncbi.nlm.nih.gov/pubmed/27363720
http://dx.doi.org/10.1111/acel.12502