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Prostaglandin I(2) upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

Cyclooxygenase‐2 (COX‐2) has been recently identified to be involved in the pathogenesis of Alzheimer's disease (AD). Yet, the role of an important COX‐2 metabolic product, prostaglandin (PG) I(2), in the pathogenesis of AD remains unknown. Using human‐ and mouse‐derived neuronal cells as well...

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Detalles Bibliográficos
Autores principales: Wang, Pu, Guan, Pei‐Pei, Guo, Jing‐Wen, Cao, Long‐Long, Xu, Guo‐Biao, Yu, Xin, Wang, Yue, Wang, Zhan‐You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013024/
https://www.ncbi.nlm.nih.gov/pubmed/27240539
http://dx.doi.org/10.1111/acel.12495