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Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans
Dysregulation of splicing factor expression and altered alternative splicing are associated with aging in humans and other species, and also with replicative senescence in cultured cells. Here, we assess whether expression changes of key splicing regulator genes and consequent effects on alternative...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013025/ https://www.ncbi.nlm.nih.gov/pubmed/27363602 http://dx.doi.org/10.1111/acel.12499 |