Intranasal insulin alleviates cognitive deficits and amyloid pathology in young adult APPswe/PS1dE9 mice

Brain insulin signaling deficits contribute to multiple pathological features of Alzheimer's disease (AD). Although intranasal insulin has shown efficacy in patients with AD, the underlying mechanisms remain largely unillustrated. Here, we demonstrate that intranasal insulin improves cognitive...

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Detalles Bibliográficos
Autores principales: Mao, Yan‐Fang, Guo, Zhangyu, Zheng, Tingting, Jiang, Yasi, Yan, Yaping, Yin, Xinzhen, Chen, Yanxing, Zhang, Baorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013027/
https://www.ncbi.nlm.nih.gov/pubmed/27457264
http://dx.doi.org/10.1111/acel.12498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013027/
https://www.ncbi.nlm.nih.gov/pubmed/27457264
http://dx.doi.org/10.1111/acel.12498

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