Decreased Endomorphin-2 and μ-Opioid Receptor in the Spinal Cord Are Associated with Painful Diabetic Neuropathy

Painful diabetic neuropathy (PDN) is one of the most common complications in the early stage of diabetes mellitus (DM). Endomorphin-2 (EM2) selectively activates the μ-opioid receptor (MOR) and subsequently induces antinociceptive effects in the spinal dorsal horn. However, the effects of EM2-MOR in...

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Detalles Bibliográficos
Autores principales: Kou, Zhen-Zhen, Wan, Fa-Ping, Bai, Yang, Li, Chun-Yu, Hu, Jia-Chen, Zhang, Guo-Tao, Zhang, Ting, Chen, Tao, Wang, Ya-Yun, Li, Hui, Li, Yun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013037/
https://www.ncbi.nlm.nih.gov/pubmed/27656127
http://dx.doi.org/10.3389/fnmol.2016.00080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013037/
https://www.ncbi.nlm.nih.gov/pubmed/27656127
http://dx.doi.org/10.3389/fnmol.2016.00080

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