Cargando…
Decreased Endomorphin-2 and μ-Opioid Receptor in the Spinal Cord Are Associated with Painful Diabetic Neuropathy
Painful diabetic neuropathy (PDN) is one of the most common complications in the early stage of diabetes mellitus (DM). Endomorphin-2 (EM2) selectively activates the μ-opioid receptor (MOR) and subsequently induces antinociceptive effects in the spinal dorsal horn. However, the effects of EM2-MOR in...
Autores principales: | Kou, Zhen-Zhen, Wan, Fa-Ping, Bai, Yang, Li, Chun-Yu, Hu, Jia-Chen, Zhang, Guo-Tao, Zhang, Ting, Chen, Tao, Wang, Ya-Yun, Li, Hui, Li, Yun-Qing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013037/ https://www.ncbi.nlm.nih.gov/pubmed/27656127 http://dx.doi.org/10.3389/fnmol.2016.00080 |
Ejemplares similares
-
Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats
por: Wan, Fa-Ping, et al.
Publicado: (2017) -
Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat
por: Wu, Zhen-Yu, et al.
Publicado: (2017) -
Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors
por: Zhang, Xin, et al.
Publicado: (2022) -
Morphological investigations of endomorphin-2 and spinoparabrachial projection neurons in the spinal dorsal horn of the rat
por: Yin, Jun-Bin, et al.
Publicado: (2022) -
Synaptic Connections between Endomorphin 2-Immunoreactive Terminals and μ-Opioid Receptor-Expressing Neurons in the Sacral Parasympathetic Nucleus of the Rat
por: Dou, Xiao Liang, et al.
Publicado: (2013)