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Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport

Selective estrogen receptor modulators (SERMs) are widely prescribed drugs that alter cellular and whole-body cholesterol homeostasis. Here we evaluate the effect of SERMs on the macrophage-specific reverse cholesterol transport (M-RCT) pathway, which is mediated by HDL. Treatment of human and mouse...

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Detalles Bibliográficos
Autores principales: Fernández-Suárez, María E., Escolà-Gil, Joan C., Pastor, Oscar, Dávalos, Alberto, Blanco-Vaca, Francisco, Lasunción, Miguel A., Martínez-Botas, Javier, Gómez-Coronado, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013287/
https://www.ncbi.nlm.nih.gov/pubmed/27601313
http://dx.doi.org/10.1038/srep32105