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Fluorescence-Based Flow Sorting in Parallel with Transposon Insertion Site Sequencing Identifies Multidrug Efflux Systems in Acinetobacter baumannii

Multidrug efflux pumps provide clinically significant levels of drug resistance in a number of Gram-negative hospital-acquired pathogens. These pathogens frequently carry dozens of genes encoding putative multidrug efflux pumps. However, it can be difficult to determine how many of these pumps actua...

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Detalles Bibliográficos
Autores principales: Hassan, Karl A., Cain, Amy K., Huang, TaoTao, Liu, Qi, Elbourne, Liam D. H., Boinett, Christine J., Brzoska, Anthony J., Li, Liping, Ostrowski, Martin, Nhu, Nguyen Thi Khanh, Nhu, Tran Do Hoang, Baker, Stephen, Parkhill, Julian, Paulsen, Ian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013296/
https://www.ncbi.nlm.nih.gov/pubmed/27601573
http://dx.doi.org/10.1128/mBio.01200-16