Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study

OBJECTIVES: There is no consensus on whether studies with no observed events in the treatment and control arms, the so-called both-armed zero-event studies, should be included in a meta-analysis of randomised controlled trials (RCTs). Current analytic approaches handled them differently depending on...

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Detalles Bibliográficos
Autores principales: Cheng, Ji, Pullenayegum, Eleanor, Marshall, John K, Iorio, Alfonso, Thabane, Lehana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Research Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013416/
https://www.ncbi.nlm.nih.gov/pubmed/27531725
http://dx.doi.org/10.1136/bmjopen-2015-010983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013416/
https://www.ncbi.nlm.nih.gov/pubmed/27531725
http://dx.doi.org/10.1136/bmjopen-2015-010983

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