TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells

Doxorubicin (Dox, Adriamycin) has been widely used in breast cancer treatment. But its severe cardio-toxic side effects limited the clinical use. Dox treatment can induce DNA damage and other accompanying effects in cancer cells, and subsequently activates nuclear factor κB (NF-κB) pathway which has...

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Detalles Bibliográficos
Autores principales: Wang, Zhenyu, Zhang, Huiyuan, Shi, Minghao, Yu, Yang, Wang, Hao, Cao, Wen-Ming, Zhao, Yanling, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013439/
https://www.ncbi.nlm.nih.gov/pubmed/27599572
http://dx.doi.org/10.1038/srep32737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013439/
https://www.ncbi.nlm.nih.gov/pubmed/27599572
http://dx.doi.org/10.1038/srep32737

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