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TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells

Doxorubicin (Dox, Adriamycin) has been widely used in breast cancer treatment. But its severe cardio-toxic side effects limited the clinical use. Dox treatment can induce DNA damage and other accompanying effects in cancer cells, and subsequently activates nuclear factor κB (NF-κB) pathway which has...

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Detalles Bibliográficos
Autores principales:	Wang, Zhenyu, Zhang, Huiyuan, Shi, Minghao, Yu, Yang, Wang, Hao, Cao, Wen-Ming, Zhao, Yanling, Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013439/ https://www.ncbi.nlm.nih.gov/pubmed/27599572 http://dx.doi.org/10.1038/srep32737

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