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Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses
BACKGROUND: Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe in smokers. The mechanism of the increased risk an...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013564/ https://www.ncbi.nlm.nih.gov/pubmed/27604339 http://dx.doi.org/10.1186/s12931-016-0428-2 |