Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses

BACKGROUND: Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe in smokers. The mechanism of the increased risk an...

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Detalles Bibliográficos
Autores principales: Wu, Wenxin, Zhang, Wei, Booth, J. Leland, Hutchings, David C., Wang, Xiaoqiu, White, Vicky L., Youness, Houssein, Cross, Cory D., Zou, Ming-Hui, Burian, Dennis, Metcalf, Jordan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013564/
https://www.ncbi.nlm.nih.gov/pubmed/27604339
http://dx.doi.org/10.1186/s12931-016-0428-2

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