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A proposed preventive role for Gamma-hydroxybutyrate (Xyrem(R)) in Alzheimer’s disease
Gamma-hydroxybutyrate (GHB or Xyrem(R)) is frequently used in humans for several clinical indications, including anesthesia, narcolepsy/cataplexy, and alcohol-withdrawal symptoms. Pharmacological effects induced in the brain by therapeutic doses of Xyrem(R) are generally GABAergic-dependent. These e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013588/ https://www.ncbi.nlm.nih.gov/pubmed/27601032 http://dx.doi.org/10.1186/s13195-016-0205-y |