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A proposed preventive role for Gamma-hydroxybutyrate (Xyrem(R)) in Alzheimer’s disease

Gamma-hydroxybutyrate (GHB or Xyrem(R)) is frequently used in humans for several clinical indications, including anesthesia, narcolepsy/cataplexy, and alcohol-withdrawal symptoms. Pharmacological effects induced in the brain by therapeutic doses of Xyrem(R) are generally GABAergic-dependent. These e...

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Detalles Bibliográficos
Autores principales:	Maitre, Michel, Klein, Christian, Mensah-Nyagan, Ayikoe G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Viewpoint
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013588/ https://www.ncbi.nlm.nih.gov/pubmed/27601032 http://dx.doi.org/10.1186/s13195-016-0205-y

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