A comparison of intrathecal magnesium and ketamine in attenuating remifentanil-induced hyperalgesia in rats

BACKGROUND: Activation of NMDA receptors play an important role in the development of remifentanil-induced hyperalgesia. We hypothesized that in addition to ketamine, intrathecal MgSO(4) could also relieve thermal and mechanical hyperalgesia in rats. METHODS: Initially, 24 Sprague–Dawley rats were d...

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Detalles Bibliográficos
Autores principales: Sun, Jiehao, Lin, Hai, Feng, Xiaona, Dong, Jiaojiao, Ansong, Emmanuel, Xu, Xuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013621/
https://www.ncbi.nlm.nih.gov/pubmed/27599837
http://dx.doi.org/10.1186/s12871-016-0235-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013621/
https://www.ncbi.nlm.nih.gov/pubmed/27599837
http://dx.doi.org/10.1186/s12871-016-0235-9

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