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A comparison of intrathecal magnesium and ketamine in attenuating remifentanil-induced hyperalgesia in rats

BACKGROUND: Activation of NMDA receptors play an important role in the development of remifentanil-induced hyperalgesia. We hypothesized that in addition to ketamine, intrathecal MgSO(4) could also relieve thermal and mechanical hyperalgesia in rats. METHODS: Initially, 24 Sprague–Dawley rats were d...

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Detalles Bibliográficos
Autores principales:	Sun, Jiehao, Lin, Hai, Feng, Xiaona, Dong, Jiaojiao, Ansong, Emmanuel, Xu, Xuzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013621/ https://www.ncbi.nlm.nih.gov/pubmed/27599837 http://dx.doi.org/10.1186/s12871-016-0235-9

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