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BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2

STUDY QUESTION: Do changes in the expression of bone morphogenetic proteins (BMPs) 2 and 4, and their antagonists Gremlin1 (GREM1) and Gremlin2 (GREM2) during human fetal ovarian development impact on BMP pathway activity and lead to changes in gene expression that may influence the fate and/or func...

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Detalles Bibliográficos
Autores principales: Bayne, Rosemary A., Donnachie, Douglas J., Kinnell, Hazel L., Childs, Andrew J., Anderson, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013871/
https://www.ncbi.nlm.nih.gov/pubmed/27385727
http://dx.doi.org/10.1093/molehr/gaw044