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L(1) regularization facilitates detection of cell type-specific parameters in dynamical systems
Motivation: A major goal of drug development is to selectively target certain cell types. Cellular decisions influenced by drugs are often dependent on the dynamic processing of information. Selective responses can be achieved by differences between the involved cell types at levels of receptor, sig...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013918/ https://www.ncbi.nlm.nih.gov/pubmed/27587694 http://dx.doi.org/10.1093/bioinformatics/btw461 |