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Association of Bactericidal Dysfunction of Paneth Cells in Streptozocin-Induced Diabetic Mice with Insulin Deficiency

BACKGROUND: Type 1 diabetes mellitus (T1DM) is associated with increased risks of enteric infection. Paneth cells constitute the first line of the gut defense. Little is known about the impact of T1DM on the bactericidal function of intestinal Paneth cells. MATERIAL/METHODS: A T1DM mouse model was i...

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Detalles Bibliográficos
Autores principales: Yu, Tao, Yang, Hong-Sheng, Lu, Xi-Ji, Xia, Zhong-Sheng, Ouyang, Hui, Shan, Ti-Dong, Huang, Can-Ze, Chen, Qi-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013981/
https://www.ncbi.nlm.nih.gov/pubmed/27572949
http://dx.doi.org/10.12659/MSM.897270