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Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction
Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014067/ https://www.ncbi.nlm.nih.gov/pubmed/27581482 http://dx.doi.org/10.1098/rsif.2016.0409 |