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Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep

Creating valid mouse models of slowly progressing human neurological diseases is challenging, not least because the short lifespan of rodents confounds realistic modelling of disease time course. With their large brains and long lives, sheep offer significant advantages for translational studies of...

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Detalles Bibliográficos
Autores principales: Perentos, Nicholas, Martins, Amadeu Q., Watson, Thomas C., Bartsch, Ullrich, Mitchell, Nadia L., Palmer, David N., Jones, Matthew W., Morton, A. Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014075/
https://www.ncbi.nlm.nih.gov/pubmed/25724202
http://dx.doi.org/10.1093/brain/awv026