Seizure suppression through manipulating splicing of a voltage-gated sodium channel

Seizure can result from increased voltage-gated persistent sodium current expression. Although many clinically-approved antiepileptic drugs target voltage-gated persistent sodium current, none exclusively repress this current without also adversely affecting the transient voltage-gated sodium curren...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Wei-Hsiang, He, Miaomiao, Baines, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014079/
https://www.ncbi.nlm.nih.gov/pubmed/25681415
http://dx.doi.org/10.1093/brain/awv012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014079/
https://www.ncbi.nlm.nih.gov/pubmed/25681415
http://dx.doi.org/10.1093/brain/awv012

Ejemplares similares