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Seizure suppression through manipulating splicing of a voltage-gated sodium channel
Seizure can result from increased voltage-gated persistent sodium current expression. Although many clinically-approved antiepileptic drugs target voltage-gated persistent sodium current, none exclusively repress this current without also adversely affecting the transient voltage-gated sodium curren...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014079/ https://www.ncbi.nlm.nih.gov/pubmed/25681415 http://dx.doi.org/10.1093/brain/awv012 |