Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond–Blackfan anaemia

Diamond–Blackfan anaemia (DBA) is a rare congenital disease causing severe anaemia and progressive bone marrow failure. The majority of patients carry mutations in ribosomal proteins, which leads to depletion of erythroid progenitors in the bone marrow. As many as 40% of all DBA patients receive glu...

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Detalles Bibliográficos
Autores principales: Sjögren, Sara E., Siva, Kavitha, Soneji, Shamit, George, Amee J., Winkler, Marcus, Jaako, Pekka, Wlodarski, Marcin, Karlsson, Stefan, Hannan, Ross D., Flygare, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Haematological Malignancy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014181/
https://www.ncbi.nlm.nih.gov/pubmed/26305041
http://dx.doi.org/10.1111/bjh.13632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014181/
https://www.ncbi.nlm.nih.gov/pubmed/26305041
http://dx.doi.org/10.1111/bjh.13632

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