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Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling

Activation of Src Family Kinase (SFK) signaling is required for the increase in endothelial permeability induced by a variety of cytokines and growth factors. However, we previously demonstrated that activation of endogenous SFKs by expression of dominant negative C-terminal Src Kinase (DN-Csk) is n...

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Detalles Bibliográficos
Autores principales: Adam, Alejandro P., Lowery, Anthony M., Martino, Nina, Alsaffar, Hiba, Vincent, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014308/
https://www.ncbi.nlm.nih.gov/pubmed/27603666
http://dx.doi.org/10.1371/journal.pone.0161975