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A B-Cell Superantigen Induces the Apoptosis of Murine and Human Malignant B Cells

B-cell superantigens (Sags) bind to conserved sites of the VH or VL regions of immunoglobulin molecules outside their complementarity-determining regions causing the apoptosis of normal cognate B cells. No attempts to investigate whether B-cell Sags are able to induce the apoptosis of cognate malign...

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Detalles Bibliográficos
Autores principales: Lorenzo, Daniela, Duarte, Alejandra, Mundiñano, Juliana, Berguer, Paula, Nepomnaschy, Irene, Piazzon, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014328/
https://www.ncbi.nlm.nih.gov/pubmed/27603942
http://dx.doi.org/10.1371/journal.pone.0162456