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Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer

Adipocytes promote progression of multiple cancers, but their role in pancreatic intraepithelial neoplasia (PanIN) and ductal adenocarcinoma (PDAC) is poorly defined. Nutrient transfer is a mechanism underlying stromal cell-cancer crosstalk. We studied the role of adipocytes in regulating in vitro P...

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Detalles Bibliográficos
Autores principales: Meyer, Kevin A., Neeley, Christopher K., Baker, Nicki A., Washabaugh, Alexandra R., Flesher, Carmen G., Nelson, Barbara S., Frankel, Timothy L., Lumeng, Carey N., Lyssiotis, Costas A., Wynn, Michelle L., Rhim, Andrew D., O’Rourke, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014359/
https://www.ncbi.nlm.nih.gov/pubmed/27617308
http://dx.doi.org/10.1016/j.bbrep.2016.06.004