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Cigarette Smoke Induces Immune Responses to Vimentin in both, Arthritis-Susceptible and -Resistant Humanized Mice

Rheumatoid arthritis (RA) is an autoimmune disease marked by chronic synovial inflammation and both, genetic and environmental factors are involved in its pathogenesis. Human leukocyte antigen (HLA) DRB1*0401 is associated with susceptibility to develop RA, while cigarette smoke (CS) exposure promot...

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Detalles Bibliográficos
Autores principales: Bidkar, Mitali, Vassallo, Robert, Luckey, David, Smart, Michele, Mouapi, Kelly, Taneja, Veena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014446/
https://www.ncbi.nlm.nih.gov/pubmed/27602574
http://dx.doi.org/10.1371/journal.pone.0162341