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Anti-VP6 VHH: An Experimental Treatment for Rotavirus A-Associated Disease

Species A Rotaviruses (RVA) remain a leading cause of mortality in children under 5 years of age. Current treatment options are limited. We assessed the efficacy of two VP6-specific llama-derived heavy chain antibody fragments (VHH) -2KD1 and 3B2- as an oral prophylactic and therapeutic treatment ag...

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Detalles Bibliográficos
Autores principales: Maffey, Lucía, Vega, Celina G., Miño, Samuel, Garaicoechea, Lorena, Parreño, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014449/
https://www.ncbi.nlm.nih.gov/pubmed/27603013
http://dx.doi.org/10.1371/journal.pone.0162351