Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer

The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 binding to laminin is of high therapeutical in...

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Detalles Bibliográficos
Autores principales: Berg, Katharina, Lange, Tobias, Mittelberger, Florian, Schumacher, Udo, Hahn, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014452/
https://www.ncbi.nlm.nih.gov/pubmed/26978578
http://dx.doi.org/10.1038/mtna.2016.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014452/
https://www.ncbi.nlm.nih.gov/pubmed/26978578
http://dx.doi.org/10.1038/mtna.2016.10

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