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Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

TNF-related apoptosis-inducing ligand (TRAIL) is a promising antitumor agent for its remarkable ability to selectively induce apoptosis in cancer cells, without affecting the viability of healthy bystander cells. The TRAIL tumor suppressor pathway is deregulated in many human malignancies including...

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Detalles Bibliográficos
Autores principales: Iaboni, Margherita, Russo, Valentina, Fontanella, Raffaela, Roscigno, Giuseppina, Fiore, Danilo, Donnarumma, Elvira, Esposito, Carla Lucia, Quintavalle, Cristina, Giangrande, Paloma H, de Franciscis, Vittorio, Condorelli, Gerolama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014461/
https://www.ncbi.nlm.nih.gov/pubmed/27111415
http://dx.doi.org/10.1038/mtna.2016.5