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Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL
TNF-related apoptosis-inducing ligand (TRAIL) is a promising antitumor agent for its remarkable ability to selectively induce apoptosis in cancer cells, without affecting the viability of healthy bystander cells. The TRAIL tumor suppressor pathway is deregulated in many human malignancies including...
Autores principales: | Iaboni, Margherita, Russo, Valentina, Fontanella, Raffaela, Roscigno, Giuseppina, Fiore, Danilo, Donnarumma, Elvira, Esposito, Carla Lucia, Quintavalle, Cristina, Giangrande, Paloma H, de Franciscis, Vittorio, Condorelli, Gerolama |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014461/ https://www.ncbi.nlm.nih.gov/pubmed/27111415 http://dx.doi.org/10.1038/mtna.2016.5 |
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