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An Efficient Method for Generation of Transgenic Rats Avoiding Embryo Manipulation

Although rats are preferred over mice as an animal model, transgenic animals are generated predominantly using mouse embryos. There are limitations in the generation of transgenic rat by embryo manipulation. Unlike mouse embryos, most of the rat embryos do not survive after male pronuclear DNA injec...

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Detalles Bibliográficos
Autores principales: Pradhan, Bhola Shankar, Majumdar, Subeer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014465/
https://www.ncbi.nlm.nih.gov/pubmed/27111419
http://dx.doi.org/10.1038/mtna.2016.9