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Experimental evolution of an RNA virus in cells with innate immunity defects

Experimental evolution studies have shown that RNA viruses respond rapidly to directional selection and thus can adapt efficiently to changes in host cell tropism, antiviral drugs, or other imposed selective pressures. However, the evolution of RNA viruses under relaxed selection has been less exten...

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Detalles Bibliográficos
Autores principales: Hernández-Alonso, Pablo, Garijo, Raquel, Cuevas, José M., Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014476/
https://www.ncbi.nlm.nih.gov/pubmed/27774280
http://dx.doi.org/10.1093/ve/vev008