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Experimental evolution of an RNA virus in cells with innate immunity defects
Experimental evolution studies have shown that RNA viruses respond rapidly to directional selection and thus can adapt efficiently to changes in host cell tropism, antiviral drugs, or other imposed selective pressures. However, the evolution of RNA viruses under relaxed selection has been less exten...
Autores principales: | Hernández-Alonso, Pablo, Garijo, Raquel, Cuevas, José M., Sanjuán, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014476/ https://www.ncbi.nlm.nih.gov/pubmed/27774280 http://dx.doi.org/10.1093/ve/vev008 |
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