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Effect of mismatch repair on the mutation rate of bacteriophage ϕX174

Viral mutation rates vary widely in nature, yet the mechanistic and evolutionary determinants of this variability remain unclear. Small DNA viruses mutate orders of magnitude faster than their hosts despite using host-encoded polymerases for replication, which suggests these viruses may avoid post-r...

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Detalles Bibliográficos
Autores principales: Pereira-Gómez, Marianoel, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014478/
https://www.ncbi.nlm.nih.gov/pubmed/27774282
http://dx.doi.org/10.1093/ve/vev010