Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation

The genetic diversity of the influenza virus hinders the use of broad spectrum antiviral drugs and favors the appearance of resistant strains. Single-stranded DNA aptamers represent an innovative approach with potential application as antiviral compounds. The mRNAs of influenza virus possess a 5′cap...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodriguez, Paloma, Pérez-Morgado, M Isabel, Gonzalez, Víctor M, Martín, M Elena, Nieto, Amelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014521/
https://www.ncbi.nlm.nih.gov/pubmed/27070300
http://dx.doi.org/10.1038/mtna.2016.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014521/
https://www.ncbi.nlm.nih.gov/pubmed/27070300
http://dx.doi.org/10.1038/mtna.2016.20

Ejemplares similares