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Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism

Peptide nucleic acids (PNAs) are synthetic oligonucleotides with many applications. Compared with DNA, PNAs bind their complementary DNA strand with higher specificity and strength, an attribute that can make it an effective polymerase chain reaction clamp. A growing body of work has demonstrated th...

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Detalles Bibliográficos
Autores principales: Hong, Christopher S, Yang, Chunzhang, Zhuang, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014523/
https://www.ncbi.nlm.nih.gov/pubmed/27115839
http://dx.doi.org/10.1038/mtna.2016.22