In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9

The ability to selectively target disease-related tissues with molecules is critical to the design of effective therapeutic and diagnostic reagents. Recognizing the differences between the in vivo environment and in vitro conditions, we employed an in vivo selection strategy to identify RNA aptamers...

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Detalles Bibliográficos
Autores principales: Mi, Jing, Ray, Partha, Liu, Jenny, Kuan, Chien-Tsun, Xu, Jennifer, Hsu, David, Sullenger, Bruce A, White, Rebekah R, Clary, Bryan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014527/
https://www.ncbi.nlm.nih.gov/pubmed/27115840
http://dx.doi.org/10.1038/mtna.2016.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014527/
https://www.ncbi.nlm.nih.gov/pubmed/27115840
http://dx.doi.org/10.1038/mtna.2016.27

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