Electroporation Enhanced Effect of Dystrophin Splice Switching PNA Oligomers in Normal and Dystrophic Muscle

Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been reported. As a possible modality for improvem...

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Detalles Bibliográficos
Autores principales: Brolin, Camilla, Shiraishi, Takehiko, Hojman, Pernille, Krag, Thomas O, Nielsen, Peter E, Gehl, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014535/
https://www.ncbi.nlm.nih.gov/pubmed/26623939
http://dx.doi.org/10.1038/mtna.2015.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014535/
https://www.ncbi.nlm.nih.gov/pubmed/26623939
http://dx.doi.org/10.1038/mtna.2015.41

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