Development of a Safeguard System Using an Episomal Mammalian Artificial Chromosome for Gene and Cell Therapy

The development of a safeguard system to remove tumorigenic cells would allow safer clinical applications of stem cells for the treatment of patients with an intractable disease including genetic disorders. Such safeguard systems should not disrupt the host genome and should have long-term stability...

Descripción completa

Detalles Bibliográficos
Autores principales: Uno, Narumi, Uno, Katsuhiro, Komoto, Shinya, Suzuki, Teruhiko, Hiratsuka, Masaharu, Osaki, Mitsuhiko, Kazuki, Yasuhiro, Oshimura, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014537/
https://www.ncbi.nlm.nih.gov/pubmed/26670279
http://dx.doi.org/10.1038/mtna.2015.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014537/
https://www.ncbi.nlm.nih.gov/pubmed/26670279
http://dx.doi.org/10.1038/mtna.2015.45

Ejemplares similares