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A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes

The modifications occurring to CaaX proteins have largely been established using few reporter molecules (e.g. Ras, yeast a-factor mating pheromone). These proteins undergo three coordinated COOH-terminal events: isoprenylation of the cysteine, proteolytic removal of aaX, and COOH-terminal methylatio...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Emily R, Cheng, Michael, Zhao, Peng, Kim, June H, Wells, Lance, Schmidt, Walter K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014548/
https://www.ncbi.nlm.nih.gov/pubmed/27525482
http://dx.doi.org/10.7554/eLife.15899