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Environmentally Endemic Pseudomonas aeruginosa Strains with Mutations in lasR Are Associated with Increased Disease Severity in Corneal Ulcers

The Steroids for Corneal Ulcers Trial (SCUT) was a multicenter, international study of bacterial keratitis in which 101 Pseudomonas aeruginosa infections were treated. Twenty-two of 101 P. aeruginosa isolates collected had a colony morphology characteristic of a loss-of-function mutation in lasR, th...

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Detalles Bibliográficos
Autores principales: Hammond, John H., Hebert, Wesley P., Naimie, Amanda, Ray, Kathryn, Van Gelder, Rachel D., DiGiandomenico, Antonio, Lalitha, Prajna, Srinivasan, Muthiah, Acharya, Nisha R., Lietman, Thomas, Hogan, Deborah A., Zegans, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014915/
https://www.ncbi.nlm.nih.gov/pubmed/27631025
http://dx.doi.org/10.1128/mSphere.00140-16