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Differential Regulation of the Extracellular Cysteine/Cystine Redox State (E(h)CySS) by Lung Fibroblasts from Young and Old Mice

Aging is associated with progressive oxidation of plasma cysteine (Cys)/cystine (CySS) redox state, expressed as E(h)CySS. Cultured cells condition their media to reproduce physiological E(h)CySS, but it is unknown whether aged cells produce a more oxidized extracellular environment reflective of th...

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Detalles Bibliográficos
Autores principales: Watson, Walter H., Burke, Tom J., Zelko, Igor N., Torres-González, Edilson, Ritzenthaler, Jeffrey D., Roman, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014973/
https://www.ncbi.nlm.nih.gov/pubmed/27642492
http://dx.doi.org/10.1155/2016/1561305